Frontline Anti-Flea and Anti-Tick Dog

Frontline Anti-Flea and Anti-Tick Dog

Ticks live in urban parks and gardens as well as rural areas, so your dog can get ticks no matter where you live. To protect your dog against these blood-sucking parasites, Frontline is what you need. FRONT LINE Flea & Tick Control is a veterinarian recommended one-time solution for the treatment and prevention of flea and tick infestations and for the control of biting lice in dogs.

What is FRONTLINE for dogs?

The Frontline brand offers three ranges of products against parasites: the range Sprays which helps fight against parasites in dogs and cats, the range Tri-Act which helps fight against fleas and ticks in dogs and finally the range Combo which helps fight against fleas, ticks and lice in dogs, cats and ferrets.

Frontline Spray

Frontline SPRAY for dogs

FRONTLINE Spray for dogs is the original flea and tick formula first used by veterinarians and now available without a prescription. It provides fast, long-lasting, waterproof treatment and control of fleas, ticks and lice for adult dogs and cats as well as puppies and kittens 8 weeks or older. FRONTLINE Spray stops existing infestations and anticipates new contamination by killing fleas, ticks and chewing lice for at least 30 days. FRONTLINE Spray can protect dogs against fleas for up to 90 days. With the active ingredient fipronil, it is available in bottles of 100, 250 and 500 ml. It is the ideal complement to pipettes.

Once applied, the treatment will protect animals against fleas, ticks and lice. It is to be used monthly and throughout the year.


Against fleas

  • Kills fleas
  • Kills newly emerged adult fleas before they lay eggs
  • Kills existing infestations on your dog's body and prevents the establishment of new infestations
  • Kills fleas that can cause flea allergic dermatitis

Against lice

  • Quickly eliminates chewing lice infestations

Against mites

  • Helps fight sarcoptic mange infestations in dogs

Against ticks

  • Tue  ticks (larva, pupa and adult) at all life stages, including brown dog ticks (Rhipicephalus sanguineus), American dog ticks (Dermacentor variabilis), solitary ticks (Amblyomma americanum) and deer ticks (Ixodes scapularis)
  • Kills ticks that can transmit Lyme disease, ehrlichiosis, babesiosis, anaplasmosis, hemobartonellosis and other tick-borne diseases


To avoid harm to you and your pet, read the package leaflet and attached instructions completely before each use. Carefully follow all instructions and warnings listed therein. Use Frontline spray only on dogs and cats over 8 weeks old. To kill fleas at all stages of their life: brown ticks, American ticks, solitary star tick, deer ticks (which can transmit Lyme disease) and dog lice, apply FRONTLINE spray for dogs, cats, puppies or kittens as follows:

  1. Wear household latex gloves.
  2. Hold the vial in an upright position. Ruffle the animal's coat with one hand while applying frontline spray to the animal's back, sides, abdomen, legs, shoulders and neck. Apply spray mist until the animal's hair is damp or thoroughly wet. 1 spray is necessary to cover 166 g of body weight of the animal and therefore allow approximately 6 sprays / kg, up to 12 / kg when the animal has long hair. Animals with long or dense hair will require the higher rate. 
  3. For the head and around the eyes, spray FRONTLINE on a gloved hand and rub gently on the animal's hair while avoiding its mouth.

Precautions of use

Do not put this product in your pet's eyes or mouth. To prevent buildup or reinfestation of fleas, use FRONTLINE Spray before the start of flea season and once a month thereafter. Ticks do not need to be sprayed directly on their body for complete control. Several monthly treatments are recommended for the elimination of mites. Do not reapply the spray for 30 days.

FRONTLINE Spray remains effective even after a bath, immersion in water or exposure to the sun. Avoid contact with human skin, eyes or clothing. Wash hands thoroughly with soap and water after handling and before eating, drinking, chewing gum, or using tobacco. Persons applying this product should wear household latex gloves.

Be careful not to use it on rabbits or other animals.

Side effects

Frontline Spray is intended for external use only. It is harmful if swallowed or absorbed through the skin. It can also cause acute eye irritation in dogs. Be careful not to spray in the eyes or face of the animal. Individual sensitivities, although rare, may occur after the use of any pet pesticide product.

If you notice that signs persist or worsen, do not hesitate to refer you to a veterinary. Some medications can also interact with pesticides. Consult a veterinarian before using this product on treated, debilitated, aged, pregnant or nursing animals.

Frontline eyedropper


FRONTLINE TRI-ACT is specially designed for the treatment and protection against infestations by fleas and ticks. It's a excellent repellent (anti-feeding), approved and tested against sand flies, biting flies and/or mosquitoes. It is exclusively designed for the dog. This triple-action veterinary treatment has a unique formula that kills faster and repels more disease-carrying parasites than its leading competitor brands.

Used every 4 weeks, it's the next level in parasite control for dogs, providing long-lasting protection against flying insects as well as fleas and ticks while preventing infestations of household fleas. FRONTLINE Tri-act for dogs helps keep your dog active, healthy and happy by working against a range of common UK parasites that can transmit disease or cause irritation in your dog.

Key benefits: triple action


  • Starts killing fleas in just 5 minutes
  • Kills newly arrived fleas and ticks on your dog in 6 hours and continues to work for the duration of treatment
  • Kills mosquitoes, biting flies and sandflies


  • Repels ticks for 4 weeks
  • Helps avoid the many risks of tick-borne diseases
  • Repels flying insects for up to 5 weeks to prevent them from biting.


  • Prevents a flea infestation in your home when used every 4 weeks by killing the fleas before they can lay eggs.
  • Clinically proven and formulated specifically for dogs, FRONTLINE Tri-act for dogs is also water resistant after 48 hours - so your dog can swim and bathe occasionally while remaining protected.


The primary packaging of frontline tri-act is a thermoformed polyethylene-ethyl vinyl alcohol-polyethylene / polypropylene film. The secondary packaging consists of a plastic / aluminum blister pack with a plastic / aluminum backing. Plastic card of 1 pipette containing 4 ml of product.


FRONTLINE Tri-Act contains fipronil and permethrin. It is only recommended for dogs between 10 and 20KG. The dose recommended by veterinarians is 1 pipette of 0,5 ml per dog per month. Apply Frontline topically and never let a dog ingest it. Use a muzzle if necessary. If you keep the liquid confined to the area behind the neck and between the shoulder blades, the dog should not be able to access it, but another animal could still lick it. Use this anti flea and tick treatment every 4 weeks for optimal protection.  As with any flea control product, washing hands and exposed skin thoroughly with soap and water after use is essential.

Precautions of use

  • Store it at a temperature below 25 ° C, in a dry place and in its original packaging.
  • How to protect your dog: Weigh your animal and choose the size of pipette appropriate for its weight. For topical use only.
  • Use the treatment once a month throughout the year for continued protection against fleas and ticks. Make sure all pets in your home are treated regularly. To apply, part the fur at the base of the neck in front of the shoulder blades and apply directly to the skin.
  • Do not bathe dogs within 2 days of application, then no more than once per week.
  • Care should be taken to avoid contact of the veterinary medicinal product with the dog's eyes. It is important to first ensure that the product is applied to an area where the animal is unable to lick it, and subsequently to ensure that other animals do not lick the treatment areas and sites after the treatment. Frontline application. Finally, make sure not to apply frontline tri-act to sick or recovering animals.
  • Do not apply frontline tri-act on cats. To prevent cats from accidentally being exposed to the product, keep treated dogs away from cats until the treatment site is dry. It is important to ensure that cats do not groom application areas on a dog that has been treated with this product. In case of exposure of this type, remember to consult a veterinarian immediately.

Side effects

Some dogs had rashes, diarrhea, vomiting and seizures and these side effects were usually caused by ingestion. Frontline tri-act is harmful to the nervous system, especially if ingested. If the product is ingested by your pet, consult your veterinarian immediately. Signs of a negative reaction include headaches, dizziness and seizures.

Less severe reactions of nausea, vomiting, and weakness may be signs that your body is reacting to the toxicity. Children are especially susceptible as they are more likely to pet the dog and put their hands in their mouths, or play with dog toys and in dog areas.

Frontline Combo for dogs


Frontline combo is only available with a prescription from your veterinarian. It is used to protect dogs against infestations of fleas, ticks and biting lice. It is indicated for the treatment and prevention in dogs and cats. It also interrupts the life cycle of fleas by preventing the development of immature stages. It helps control sarcoptic mange in dogs.


Frontline Combo will even provide protection for your home! Frontline Combo combines the potent action of Fipronil (eradicates adult ticks, fleas and lice from your dog) with the preventative action of (S) -Methoprene (inhibits the development of flea eggs and larvae). Frontline Combo will therefore prevent an infestation in your home and protect your dog.


Frontline Combo is indicated for:

  • Eradicate fleas (Ctenocephalides spp.) And prevent new infestations for up to 8 weeks.
  • Prevent the expansion of fleas by stifling the growth of eggs and larvae  up to 8 weeks after application.
  • Eliminate ticks (Ixodes ricinus, Dermacentor variabilis, Rhipicephalus sanguineus) for up to 4 weeks.
  • Eliminate biting lice (Trichodectes canis).
  • Frontline Combo can be incorporated into a flea allergic dermatitis treatment program.


  • Dogs from 2 to 10 kg: a COMBO Spot-On S pipette (0,67 ml).
  • Dogs from 10 to 20 kg: a FRONTLINE COMBO Spot-On M pipette (1,34 ml).
  • Dogs from 20 to 40 kg: a FRONTLINE COMBO Spot-On L pipette (2,68 ml).
  • Dogs between 40 and 60 kg: one FRONTLINE COMBO Spot-On XL pipette (4,02 ml).

Wait at least 4 weeks after application before using Frontline Combo again.


Hold the Frontline Combo pipette in an upright position and peel off the cap with a quick motion. Keeping your dog upright, part the coat between the shoulder blades until you can see skin. Place the tip of the Frontline Combo pipette on the skin and squeeze firmly several times until the entire pipette is empty. Do this in one or two spots, depending on the size of the dog.


Do not use Frontline Combo on puppies less than 8 weeks old or weighing less than 2 kg. Do not use on sick animals (systemic diseases, fever, etc.) or on convalescing animals. Do not use on rabbits, it could be fatal.

Do not touch newly treated animals and do not allow children to play with them until the application surface is dry.

Precautions of use

  • If the flea infestation is severe, we recommend starting treatment with 6 ml / kg of Frontline Spray (this is the maximum dose and is equivalent to pumping the 250 ml and 500 ml spray bottle 4 times per kg, or 12 times per 100 ml sprays), then administer the Frontline Combo pipettes every month.
  • You may see live fleas more than 48 hours after treatment. This may be due to a recent flea re-infestation with fleas that have hatched in the dog's immediate environment. However, they will be eliminated within hours of landing on your dog.
  • Bathing your dog with shampoo before using the treatment will not reduce its effectiveness, but be careful not to bathe the dog for two days after the treatment. For more information on this flea and tick product, please contact your veterinarian.
  • Frontline Combo can be used safely on pregnant or lactating bitches.
  • We recommend treating the animal in the evening rather than during the day, and not to let the animal sleep with its owner, especially with children.
  • Do not smoke, drink or eat while applying the product to your pet.

Side effects

Side effects on our doggies can be:

  • Swelling
  • Itching
  • Irritation (applied area)
  • Excessive salivation
  • Diarrhea
  • Loss of appetite

These effects should all go away within 24 hours of applying Frontline Plus; if they persist, you should contact your veterinarian.


The entire Frontline line of care products are known for their  very effective active ingredients against fleas and ticks. There are products specially designed to prevent and control parasitic infestations on feline and canine companions. With its pros and cons, the Frontline line of care products are considered the most popular brand in flea and tick care.

The pros

More information - Frontline products are generally very easy to use. There are topical solutions that can be applied directly to your pets' fur. And there are also Frontline skincare products that come packaged in spray bottles and pipettes for spot treatments.

Efficiency - The effectiveness of the entire Frontline product line is never questioned. Most fleas and ticks usually die within 24 to 48 hours. Treatments on cats typically last a full month (30 days) while your canine companions typically enjoy 2 months parasite free after a single application. For owners of large to giant dog breeds, it is important to make sure that you purchase the correct treatment option for your pet's size.

Accessible - The prices of most Frontline Pet care products are relatively cheaper than those of other branded products.

The idiots

Use under the advice of the veterinarian - Despite newer products that can be purchased over the counter or without a prescription from the veterinarian, Frontline care products are still very powerful drugs that should be used with caution. It is not recommended for pets that may already have a flea allergy or skin infection or any other medical complication that exposes raw or bleeding skin caused by a parasite infestation.

Some side effects - There are some side effects to using any Frontline skincare product. The most common side effect is fur loss, which is especially seen in cats. Patches of fur can sometimes fall off during the 48 hour treatment period and can last for days or weeks at a time. Some companion dogs may also lose their overcoat during treatment. If this is the case, veterinarians recommend that further processing of any Frontline care product be discontinued in the future.

Once dead, most ticks will fall off naturally. If they don't, you can give them a slight pull, preferably with tweezers. If the tick doesn't come out easily, take your pet to the vet - don't pull harder as the mouthparts could stay in your pet's skin, which could lead to infection. Apply Frontline every four weeks throughout the year. It is important to use a treatment that kills ticks within 48 hours, as this minimizes the risk of transmitting a disease, such as Lyme disease. Throughout the treatment, check your pet regularly, especially after being outside.

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